• Large deformations of resection
specimen make 3D correlation with
pre-operative imaging is very difficult
• Lung lobes were inflated with
formalin to approximate the CT
volume
• Registration in two steps:
1. find correct orientation of CT with
sliced specimen; resample CT in the
same plane
2. match macroscopic slices to CT
volume
• Verify GTV volume and shape
• Identify the extent of the CTV
Stroom et al. 2007; Int J Radiat
Oncol Biol Phys. 69:267-275
3D validation of contouring with pathology