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Time-of-flight (TOF) PET

c

x

t

=∆

2

In addition to the

coincidence

information, the

difference in flight time

is registered

Better SNR

Example:

Δt=500ps

Δx=?

(a) Localization without TOF,

(b) with TOF. Townsend, PMB 2008 [3]

ESTRO Teaching Course Advanced Imaging: PET – Basic Principles

21

cm

t c

5.7

5.0

=

∆⋅ ⋅

=∆