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How To: An Approach

• Determine guidance / registration strategy up front

• Clarify Imaging Objectives

1. Prostate Boundary (CTV)

2. Implanted Markers (Guidance/registration surrogate)

3. Tumor-Dense Regions (GTV)

• Manage Prostate Motion

– Must not assume stable prostate geometry b/w acquisitions

– Trade off spatial resolution / acquisition time

– Repeat acquisition if motion blurring present

– +/- antiperistaltic agent + bowel prep

– Consider ERC

Yanke et al, 1991