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Dosimetry Literature
• +++ publications
• Absolute modeled TCP achieved by SIB ranged from 2-
15% and generally achieved with similar or small
increase to NTCP rectum
• Ability to dose escalate was anatomy dependent; lesions
within 5mm of rectal wall were difficult to dose escalate
• TCP/NTCP calculations highly dependent on accuracy of
GTV delineation
• Ability to boost independent of technique (fixed field
IMRT vs. VMAT; sequential vs. SIB) when considering
the effects of intra-fraction motion