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Caution with FDG-PET for GTV delineation
•
Local in-field recurrences can occur outside the PET-GTV.
•
FDG-PET is not suitable as an exclusive modality for GTV delineation.
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Inherently low spatial resolution functional imaging such as FDG-PET should not be
used as a surrogate for anatomical imaging.
•
Functional imaging indicates tumor biology (proliferation, hypoxia,…), rather than the
exact tumor extension.
Soto D. et al. Radiother Oncol 2008.