1580-1581 / 2351
Hyperfractionation: EORTC 22791
356 ptt
Loco‐regional control
Late effects
p = 0.02
n.s.
Improved Terapeutic Ratio:
Increase in tumour control
Increased acute toxicity (
Confl. mucositis - conv: 49%; HFX: 67%
)
But same late morbidity
Horiot 1992