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DAHANCA 18 - low dose weekly cisplatin

C-RT standard in Denmark from January 1. 2007

All

ti

D i h ti

t f

4 f 5 N ti

l HNSCC

consecu ve an s pa en s rom o a ona

centres from 2007-2010

Incusion criteria:

- UICC st III-IV, SCC,

Oral cavity larynx oropharynx hypopharynx

-

,

,

,

- GFR > 50mg/ml

- WHO performance 0 - 2

Treatment:

Radiotherapy: 66 68Gy 2Gy/F 6 F/week +

-

-

,

,

,

- Nimorazol 1200mg/m

2

. +

- Cisplatin 40mg/m

2

x 1 weekly during radiotherapy

Benzten et al Acta Oncol 2015