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DAHANCA 18 - low dose weekly cisplatin
C-RT standard in Denmark from January 1. 2007
All
ti
D i h ti
t f
4 f 5 N ti
l HNSCC
consecu ve an s pa en s rom o a ona
centres from 2007-2010
Incusion criteria:
- UICC st III-IV, SCC,
Oral cavity larynx oropharynx hypopharynx
-
,
,
,
- GFR > 50mg/ml
- WHO performance 0 - 2
Treatment:
Radiotherapy: 66 68Gy 2Gy/F 6 F/week +
-
-
,
,
,
- Nimorazol 1200mg/m
2
. +
- Cisplatin 40mg/m
2
x 1 weekly during radiotherapy
Benzten et al Acta Oncol 2015