1664-1665 / 2351
Acute mucositis : frequency
Mucositis grade 3/4 RT RT+CT Chemotherapy
RTOG 95 01*
34% 77% Cisplatin 100 mg/m2 day 1 22 43
-
,
, ,
EORTC 22931*
21% 41% Cisplatin 100 mg/m2, day 1, 22, 43
GORTEC 94-01
39% 71% Carboplatin/5-FU, three times
RTOG 91-11
24% 43% Cisplatin 100 mg/m2, day 1, 22, 43
RTOG 0522
NA 33% Cisplatin 100 mg/m2, day 1 & 22
86% used IMRT
Cooper et al. NEJM 2004
Bernier el NEJM 2001
* Huge variation from one study to another
.
Calais et al. JNCI 1999
Forastiere et al. NEJM 2003
Ang KK et al. JCO 2014