1974-1975 / 2351
FUTURE TRENDS
Clinical activity of androgen deprivation therapy in patients with
metastatic/relapsed ARpositive salivary gland cancers
L. Locati, F. Perrone, B. Cortelazzi, S. Lo Vullo, P. Bossi, G. Dagrada, P. Quattrone, C.
Bergamini, P. Potepan, E. Civelli, C. Fallai, S. Pilotti, L. Licitra
Head & Neck 2015
17 pts with relapsing and/or metastatic SGCs AR-expressing: SDC
(N=8), adenocarcinoma NOS (N=7), cystadenocarcinoma (N=1) and
poorly differentiated carcinoma originated from SDC (N=1)
All pts were homogeneously treated with ADT (
Bicalutamide +
decapeptyl)
No significant toxicities were reported.
Overall response rate was
64.7%; three
-
year PFS and 5
-
year OS were 11.8% and 19.3%,
respectively
mercoledì 29 giugno 16