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03/01/13

Recurrent disease:

diagnosis

Amenable to curative

treatment

- Pathology

- HPV

YES

NO

- Surgery: lung nodules

- (Re)-Irradiation

- Local salvage surgery

- Symptoms

- Disease burden

- Comorbidities and PS

- Prognosis (HPV)

- Patient wishes

Systemic treatment

NO

YES

Best supportive care

Best supportive care

Systemic treatment

- Platin/5-FU/cetuximab

- Clinical trial

Monotherapy

PS 0-1

PS 2