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Accuracy after (chemo)radiation for head and neck carcinoma:

Local

Sensitivity

Specificity

PET

50% - 100%

64% - 93%

Regional

Sensitivity

Specificity

PET

40% - 100%

25% - 100%

FDG-PET

Problems:

<3-4 months after (C)RT high incidence equivocal and

inaccurate interpretation (local and regional)

Problems:

False-positive: inflammatory effect

False-negative: tumors < 0.5 cm

Negative predictive value at 3 months in general very reliable

Salvage Surgery