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Normal tissue tolerance
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Serial tissue: Dose constraints
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Tolerance is not related to the irradiated volume
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Max dose
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E.g. ’max 50 Gy to spinal cord’ ’max 54 Gy to optic chiasm’
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Parallel tissue: Dose volume constraints
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Tolerance is dependent on the irradiated volume
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DVH constraints
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E.g. ’mean dose below 30 Gy to oral cavity’, ’mean dose
below 26 Gy to parotids’, ’2/3 of larynx below 50 Gy’