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Normal tissue tolerance

Serial tissue: Dose constraints

Tolerance is not related to the irradiated volume 

Max dose

E.g. ’max 50 Gy to spinal cord’ ’max 54 Gy to optic chiasm’

Parallel tissue: Dose volume constraints 

Tolerance is dependent on the irradiated volume

DVH constraints

E.g. ’mean dose below 30 Gy to oral cavity’, ’mean dose 

below 26 Gy to parotids’, ’2/3 of larynx below 50 Gy’