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Fractionation sensitivity
E l
ti
l ti
L t
ti
l ti
ar y reac ng norma ssues
•
Low fractionation
a e reac ng norma ssues
•
High fractionation
sensitivity
sensitivity
•
Small increase in tolerance
with decreasing dose per
f
i
•
Large increase in
tolerance with decreasing
d
f
i
ract on
•
High alpha beta (8 30 Gy)
ose per ract on
•
Low alpha beta (2 4 Gy)
‐
‐
•
Time factor (repopulation)
‐
‐
•
No time factor