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Conclusion fractionation
‐
•
Awareness of the fractionation sensitivity of
tumors and normal tissues is critical
•
Clinical studies and meta‐analysis have shown
that moderately accelerated radiotherapy
improves loco‐regional control
H f ti
t d RT i
l
i
l
•
yper rac ona e mproves oco‐reg ona
control and survival
•
Altered fractionation is thus recommended for
primary radiotherapy of head and neck cancer