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Summary key points

 – 

M difi d f

i

i

(h f

i

i

d/

o e ract onat on yper ract onat on an or

acceleration) is superior to conventional fractionation

Hypoxic sensitizers (e g nimorazole) improves tumor control

. . 

and survival without enhancing radiation morbidity

Concomitant platinum‐based chemotherapy is more effective 

than RT alone for younger patients in good performance 

status with and advanced stage tumours. Acute and late

toxicity is increased

EGFR inhibition combined with radiotherapy (but not 

chemoRT) results in enhancement of tumor response

The optimal combination of these ’radiotherapy intensifiers’ is 

still unsettled