Summary key points
–
M difi d f
i
i
(h f
i
i
d/
•
o e ract onat on yper ract onat on an or
acceleration) is superior to conventional fractionation
•
Hypoxic sensitizers (e g nimorazole) improves tumor control
. .
and survival without enhancing radiation morbidity
•
Concomitant platinum‐based chemotherapy is more effective
than RT alone for younger patients in good performance
status with and advanced stage tumours. Acute and late
toxicity is increased
•
EGFR inhibition combined with radiotherapy (but not
chemoRT) results in enhancement of tumor response
•
The optimal combination of these ’radiotherapy intensifiers’ is
still unsettled