VG H&N course intro Florence 2016.pptx

RISK FACTORS

•Bile – gastric reflux

•Genetic susceptibility



Alcohol metabolism

( l

f ld h d d h d

)

po ymorp sms o a e y e e y rogenase



CYP2E1



DNA repair / Cell cycle control

•Genetic syndrome

(Fanconi’s aniemia / Dyskeratosi congenita)

•Batel quid and gutka

HPV

(see below)