VG H&N course intro Florence 2016.pptx

Sinonasal Tumor - HPV

Bishop JA; Am J Surg Pathol 2013

Human papillomavirus-related carcinomas of the

sinonasal tract

• 161 sinonasal carcinomas

• 34 (21%) HPV Pos (28 SCC and variants)

• 59 (37%) p16 IHC positive

• p16 expression strongly correlate with HPV DNA presence :

• A trend toward improved survival was observed in the HPV-

iti

pos ve group