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Background
•
Staphylococcal enterotoxins are pyrogenic
proteins that lead to toxic shock and respiratory
distress due to inhalation.
•
Symptoms 90 minutes‐24 hours post aerosol
exposure fever, headache, muscle aches,
pulmonary and GI symptoms.
•
Biothreat agent due to universal availability and
lack of discernment between other syndromes
or diseases.
•
Initial aerosol exposure studies performed with
SEB only, SEA & SEC shown later to have similar
effects.
SMPR Key Points
•
Field use by DOD trained operators
•
Analytical protein detection method in
liquid samples of SEA, SEB, SEC
1
, SEC
2
,&
SEC
3
.
•
Acceptable minimum detection level
(AMDL) of 0.25ng/mL with a maximum time
t
lt f f
h
o resu o our ours.
•
Probability of detection (POD) of the
analyte shall be > 0.95.