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The Royal Marsden

PET-CT Recommendations

The routine use of PET is not recommended for the diagnosis or staging of clinical

stage I-III CRC.

PET is recommended for determining management and prognosis if conventional

imaging is equivocal for the presence of metastatic disease.

The routine use of PET is not recommended for the measurement of treatment

response in locally advanced rectal cancer before and after preoperative

chemotherapy.

PET is also not recommended for routine surveillance in patients with CRC treated with

curative surgery at high risk for recurrence.

PET is recommended to determine site of recurrence in the setting of rising CEA when

conventional work-up fails to unequivocally identify metastatic disease.

PET is recommended in the preoperative assessment of CRC liver metastasis before

surgical resection.