The Royal Marsden
PET-CT Recommendations
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The routine use of PET is not recommended for the diagnosis or staging of clinical
stage I-III CRC.
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PET is recommended for determining management and prognosis if conventional
imaging is equivocal for the presence of metastatic disease.
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The routine use of PET is not recommended for the measurement of treatment
response in locally advanced rectal cancer before and after preoperative
chemotherapy.
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PET is also not recommended for routine surveillance in patients with CRC treated with
curative surgery at high risk for recurrence.
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PET is recommended to determine site of recurrence in the setting of rising CEA when
conventional work-up fails to unequivocally identify metastatic disease.
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PET is recommended in the preoperative assessment of CRC liver metastasis before
surgical resection.