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Prodige/ACCORD 12/0450 trial

Capecitabine 800mg/m2

45 Gy CRT

S

Centre policy

Staging :- Evaluated by TRUS and/or MRI

Oxaliaplatin 50mg/m2 x 5

Capecitabine 800mg/m2

*

50.4Gy CRT

N=598

Centre policy

S

Primary end point- pCR 11% - 20% 85% power