Evidence in order of strength
Specific randomised trials (
Quasar
, EORTC 22921,
Sainato,
SCRIPT
, Chronicle, ADORE)
Composite trials (PETACC-6 and German trial)
Individual patient Meta-analyses (often selected –
some used retrospective data)
Pooled analyses
Systematic reviews
Nomograms based on randomised trials -Valentini
SCPRT 5x5Gy in Red