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Unicancer Prodige 23

NCT01804790

Capecitabine 800mg/m2

50 Gy CRT

S

depending on

ypTNM and the

center's choice

Staging :- cT3/T4 Evaluated by TRUS and/or MRI

mFolfirinox, 6 cycles then

Capecitabine 800mg/m2

Then 50 Gy CRT

N=460

depending on

ypTNM and the

center's choice

S

Primary end point- 3 Year DFS