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SQUAMOUS CELL CARCINOMA NOS ( 80 - 90% )

size of neoplastic cell

basaloid morphology

keratinization

presence of mucinous microcysts

ANAL CARCINOMA : HISTOLOGICAL

CLASSIFICATION

WHO 2

nd

Edition.

large cell keratinizing

large cell non-keratinizing

Basaloid ( cloacogenic )

degree of differentiation

presence of adjacent AIN

VERRUCOUS CARCINOMA

( GIANT CONDYLOMA OF BUSCHKE-LOWENSTEIN )

( < 1 % )

ADENOCARCINOMA

( anal gland, mucinous – fistula related, rectal type )

( 10 – 15 % )

NEUROENDOCRINE CARCINOMA ( large cell & small cell type ) ( < 2 % )