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16

Dose, volume, and time effect

5%

7%

3%

Local control at 3 years

6%

Tanderup et al, Radiotherapy and Oncology 2016

Effect of dose, volume and time:

Dose:

10Gy → 5% LC

Time:

7 days ~ 5Gy

Volume 10cm

3

~ 5Gy

85Gy for 30cm

3

CTV

HR

: 93% LC

85Gy for 20cm

3

CTV

HR

: 94% LC

85Gy for 70cm

3

CTV

HR

: 86% LC