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132 101 69 43 29 16 5 1

97 78 69 46 29 12 3 0

115 85 64 46 32 19 6 1

86 57 46 32 25 15 4 2

Frequency G≥2 and

EMBRACE I cohort

5 centers included

Patients with Bladder wall infiltration excluded

Patients with Baseline morbidity assessment

and at least one Follow Up included

451 patients

CTC Grade

0

172

1

213

2

50

3

4

ICRU bladder point dose

representing bladder trigonum dose

Dose constraint:

<76 Gy

Up to 12% G≥2

Work in progress:

Spampinato, Tanderup et al. Work in progress