Slide 1

GTV = Gross Tumor Volume

➢

Macroscopic tumor, visible clinically and with imaging

CTV = Clinical Target Volume

➢

Tissue volume that contains a GTV and/or subclinical

microscopic malignant disease, which has to be

eliminated

ITV = Internal target volume

➢

Volume that accounts for internal inter- and intra-

fraction motion and deformation of the CTV

CTV

ITV

GTV

Definitions

(upcoming definitions in the frame of adaptive thinking)

ICRU reports 50-83

Valid for the primary tumor: GTV-T, CTV-T

for lymph nodes: no GTV-N, CTV-E (elective nodal CTV)

GTV-N, CTV-N