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Prophylactic extended-field irradiation of para-aortic lymph

nodes in stages IIB & bulky IB and IIA cervical carcinomas

Ten-year treatment results of RTOG 79-20. JAMA 1995

10 yr OS - 44% vs 55%

DFS – similar 40 vs 42%;

LRF similar - 35% vs 31%

Better Survival following first failure

Higher G 4 & 5 toxicities at 10 yrs 4% vs 8%

Death due to RT complications 1% vs 2%