388 / 1345
25
Take home message: nodal CTV
Margins add to considerable irradiation of normal tissue
PTV margin for elective target volume:
7-10mm margin without daily image guidance
5mm margin with daily image guidance and bony fusion
Potential in pelvic elective radiotherapy to reduce irradiated
volume by 40% with IMRT and daily IGRT (2500cc → 1500cc)
Pattern of nodal failure (EMBRACE)
152 failures in 1338 pts (11%)
Inside elective target volume: 41%
Outside elective target volume: 41% (39% PAO)
In boosted nodes: 35%