433 / 1345
Dose needed for lymph node metastases control
In literature still some uncertainty !
• Escalation typically recommended up to 55-60Gy
• SIB IMRT – 55Gy/25# with option of sequential boost -
10Gy/5#
• FDG avid nodal disease - 62Gy/31# SIB
Grigsby PW, et al Int J Radiat Oncol Biol Phys
2001, 49(3):733–738
.
Beadle BM, et al Int J Radiat Oncol Biol Phys 2010, 76(5):1396–1403.