• Expected short survival
•
Maranzano et al
R&O 2009
•
2x 8 Gy vs. 15 Gy /3fr + 15 Gy /5fr
•
N= 300
•
Outcome =
•
Maranzano et al
JCO 2005
•
1x 8 Gy vs. 2x 8 Gy
•
N= 305
•
Outcome =
•
SCORAD (Peter Hoskin) -> ASCO 2017
•
1x 8 Gy vs. 5x 4 Gy
•
N= 688
•
Outcome =
• Prolonged survival ?
Spinal cord compression -> published papers