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Fraction 1

4D Digital

Patient

Tumor dose

Lung dose

Esophagus

OK

Fraction 3

Robot

CT

Time = 30 seconds

Advanced in-room imaging to

update 4D digital patient

model

Online treatment adaptation to

match present 4D digital patient

model and updated treatment

objectives

4D Optimized delivery and real-

time image-guided protection of

healthy tissues

PT

Real-time dose

reconstruction

4D PGI Safety

4D Digital

Patient

Planning

M. Hoogeman