259 / 1224
/
Very limited gain in TCP for doses >100Gy BED
Grills JTO 2010; Ohiri IJROBP 2012
0
20
40
60
80 100 120 140 160 180 200
BED
10
Perscription dose PTV (Gy)
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1.0
Local control
Guckenberger Radiother Oncol 2013
= 3 x 18Gy
What dose is now actually required?
n=505
n=395
13.06.2016
Matthias Guckenberger - ESTRO SBRT Course 2016 Athens
17