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Take home message

A set-up accuracy of approximately 2 mm/1

°

for brain and 1 mm/1

°

for

spine irradiations (1 SD) has been associated with clinically relevant

parameters.

All

current immobilisation systems for brain or spine SBRT can be used,

if

properly combined with

on-line

IGRT.

Immobilisation systems associated with larger rotational errors

are not

preferred or

should be combined with a 6DOF couch correction or in

combination with multiple isocenters.

One should perform

complete end-to-end tests

to establish the complete

treatment chain accuracy and implement the appropriate CTV-PTV

margins accordingly.