Discussion: Clinical Relevance
Should we measure intra-fraction motion?
Yes, at planning in order to individualize the safety margin (and to
determine the time-averaged mean position)
Should we correct for intra-fraction motion?
Amplitude seems to have a minor effect on the margin. However,
for central lesions and lesions close to the thoracic wall the
penumbra will be sharper
Take care of small lesions and large amplitudes
Should we correct for inter-fraction motion?
YES!
Dosimetrical effects?
Be cautious for fast and single-fraction treatments