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Discussion: Clinical Relevance
Should we measure intra-fraction motion?
Yes, at planning in order to individualize the safety margin
??
And if necessary to reduce the motion amplitude with compression
Should we correct for intra-fraction motion?
The penumbra is more sharp in abdomen than in lung
Amplitude has an effect on the margin
Still systematic uncertainties dominate the required margin
Should we correct for inter-fraction motion?
YES!
Should we adapt the treatment plan?
First solve issues mentioned above