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Dokumentenname Datum Seite 33

Interplay effect

study

technique

order of magnitude

Jiang et al, 2003 IMRT, fractionated

treatment

30% for a single field, 1%-2% over 30

fractions

Court et al, 2004 IMRT, fractionated

treatment

10% if leaf motion is perpendicular or

parallele to tumor motion for all fields

Kang et al, 2010 SBRT, IMRT

Small changes in dose to the GTV

Li et al, 2013

SBRT, FFF VMAT

Small changes in the dose to the GTV

Ong et al, 2011

SBRT VMAT

Gamma agreement score >98% for 2 arcs,

above 93% for 1 arc

Rao et al, 2011

SBRT VMAT

Changes of less than 1% inside the PTV

Stambaugh, 2011 SBRT VMAT

2-3% @A=2cm, however up 16% for

extreme cases (large A and T)

Interplay has to be assessed for department specific irradiation

technique.