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Dokumentenname Datum Seite 42
Integrated boost concept: Motivation
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Single fraction limited by tolerance to the cord
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Many single fractions protocols are only for target >3mm away from
the cord (example RTOG 0613)
Fractionated approach
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Most local failures after SBRT are in the epidural space or in the
untreated vertebral elements (Nguyen 2010, Nelson 2008)
Integrated boost concept
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10-20% vertebral compression fractures in single fraction SBRT
(Boehling, 2012, Sahgal 2013)
Homogeneous prescription
SBRT spine – integrated boost concept