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Matthias Guckenberger - DEGRO 2015
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• Prostate Cancer: Multi-focal and poly-clonal disease
• HOWEVER: mono-clonal origin of metastatic spreat
• Clinically significant cancer
GS ≤ 6 w/o G pattern 4 or 5
Organ-confined disease
Tumour volume <0.5 cm
3
Liu Nat Med 2009
Ahmend NEJM 2009
Metastatic spreat of prostate cancer