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Page Background

HCC TREATED RADICALLY

AUTHOR

DESIGN

CHILD-

PUGH /

BCLC

GRADE

NUMBER OF

PATIENTS

DOSE FRACTIONATION

SCHEME

2 y

LOCAL

CONTROL

2y

/MEDIAN

SURVIVAL

Andolino

(No transplant)

2010

Retrospective

A

B

/A-C

24

13

3x12-16Gy

5x8Gy

87%

47%/

20 Months

Kang

2012

Phase II

A

B7

/A-C

41

6

3x14-20Gy

95%

69%/

Not reported

Bujold

2013

Phase I-II

A

/A-C

102

6x4-9Gy

87% at 1 y

34%/

17 Months

Bibault

2013

Retrospective

A

B

/A-C

67

8

3x8-15Gy

90%

50%/

15 Months

Sanuki

2013

Retrospective

A

B

/A

158

27

5x8Gy

5x7Gy

93%

83%/

Not reported

Park

2013

Retrospective

A

B

/A-B

19

7

10x4-5Gy

88%

67%/

Not reported

Kimura

2015

Retrospective

A

B

/A-B

56

9

4x12Gy

(peripherally located

tumors)

100%

76%/

41 Months

Su

2016

Retrospective

A

B

/A-B

114

18

42-46Gy in 3-5 fractions

or

28-30Gy in 1 fraction

84%

82%/

Not reported