Draft, Do Not Distribute
5 Approved
Variola
SMPR v7.5
Annex II: Inclusivity Panel
74
75
The inclusivity panel shall include:
76
77
·
Sequences from at least two representative strains from each major clade
78
of
Variola virus
79
·
Any other strain with differences in the assay primer and/or probe target
80
sequences based on bioinformatic analysis (Annex V).
81
82
Note: The World Health Organization (WHO) restricts access to
Variola virus
83
genomic material; use of any genomic sequences greater than 500 bp requires
84
written permission/approval from the WHO. Insertion of
Variola virus
DNA into
85
other
Orthopoxviruses
is prohibited.
86
87
More details can be found at:
88
89
90
91
