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43

Dose in D90 and HR CTV for point A prescription

High Target Doses in small tumours

Low Target Doses in large tumours

50

60

70

80

90

100

110

120

130

140

0 10 20 30 40 50 60 70 80 90 100 110

Volume HR CTV, cm

3

HR-CTV D90 standard

Standard

Violation of OAR constraint

K Tanderup et al, Radiother Oncol 2010

Tanderup et al.