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Klug F4

Klug F1

Klug F2

Klug F3

insertion 1 – fraction 1

insertion 1 – fraction 2

MRI Tuesday afternoon

MRI Wednesday morning

Impact on dose: fixed plan + variable anatomy

insertion 2 – fraction 3

insertion 2 – fraction 4

MRI Tuesday afternoon

MRI Wednesday morning

Plan 1

Plan 2

<------ intra-application variation ------>

<------ inter-application variation ------->

© Stefan Lang

Lang et al. 2013,

Radiother Oncol