Klug F4
Klug F1
Klug F2
Klug F3
insertion 1 – fraction 1
insertion 1 – fraction 2
MRI Tuesday afternoon
MRI Wednesday morning
Impact on dose: fixed plan + variable anatomy
≠
insertion 2 – fraction 3
insertion 2 – fraction 4
MRI Tuesday afternoon
MRI Wednesday morning
≠
Plan 1
Plan 2
<------ intra-application variation ------>
<------ inter-application variation ------->
© Stefan Lang
Lang et al. 2013,
Radiother Oncol