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15

EMBRACE II interventions

Increased use of IC/IS technique in BT

Reduction of vaginal source loading

Systematic utilisation of IMRT + Utilisation of daily IGRT

(reduction of V43Gy by 1000cm3 (from 2500cm3 to 1500cm3

pelvis)

EBRT target concept related to the primary tumour; concepts for

OAR contouring

EBRT dose prescription (45Gy/25fx) and reporting

Adaptation of EBRT nodal elective CTV according to risk of

nodal and systemic recurrence

Systematic application of simultaneous chemotherapy

Reduction of overall treatment time