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48 nodes, 15 patients, repeat MRI during EBRT

Position shift in 6 directions assessed

Affected nodes also change their position

Order of magnitude lower than for primary GTV

(< 10 mm)

Maximal margins (computer)

0

1

2

3

4

5

6

7

8

9

med

lat

ant

post

sup

inf

margin (ml)

Nodes also move! (a little)

Schippers M, et al. 2011

Inter-fraction motion of CTV-N

TV-T – In er al Target Volume