434 / 1726
Dose needed for lymph node metastases control
In literature still some uncertainty !
•
Escalation typically recommended up to 55-60Gy
•
SIB IMRT – 55Gy/25# with option of sequential boost -10Gy/5#
•
FDG avid nodal disease -62Gy/31# SIB
Grigsby PW, et al Int J Radiat Oncol Biol Phys 2
001, 49(3):733–738
.
Beadle BM, et al Int J Radiat Oncol Biol Phys 2010, 76(5):1396–1403.