472 / 1726
• Based on broader treatment planning experience DVH constraints could be adapted for patients
with and without nodes
• Current table is provided based on data from 52 patients and 3 centers
• Aim is that values for soft constraints should be reached in 70-80%, allowing for outliers in case
of exceptional anatomy or other planning problems
• DVH parameters are tight but feasible for different treatment planning systems
• Try to find the best balance between tumor and OAR dose!
OAR
Soft constraint
EMBRACEII protocol
planning guidelines
Percentage of
patients complying
to original
70-80
th
percentile
Updated
planning
guidelines
Bowel
No para-aortic irradiation
V40Gy (cm
3
)
V30Gy (cm
3
)
< 100
< 275
20%
28%
221 - 276
491 - 500
< 250
< 500
Bowel
Para-aortic irradiation
V40Gy (cm
3
)
V30Gy (cm
3
)
< 220
< 450
36%
29%
319 - 355
678
< 300
< 650
Bladder
V40Gy (%)
V30Gy (%)
< 55
< 80
60%
60%
60 - 69
85 - 92
< 60
< 80
Rectum
V40Gy (%)
V30Gy (%)
< 75
< 90
69%
54%
77 - 82
94 - 97
< 75
< 95
Body Conformality
(V43/Volume of PTV)
1.15
88%
1.10 - 1.11
1.10
Data September 2017
Results