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Dose to macroscopic nodal disease

Lymph node status by CT and MRI at diagnoses and after 50 Gy

Total node dose mean 55 Gy (43-60)

Good response group with node size < 10 mm after 50 Gy

Bad response group

Excellent node control

3 recurrences in good response group, no relation with dose

9/37 recurrences in bad response group, but none after > 58 Gy

58 to 60 Gy EBRT gives high control rates