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GUSTAVE ROUSSY

THÈME DU DIAPORAMA

Summary and conclusions

Radical radiation therapy : established treatment modality

Neo-adjuvant CT approaches: investigational

CRT with Cisplatin extensively tested for cervical cancer

Concomitant Chemo-radiation with wkly cisplatin (40 mg/m2) : STD of care

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CRT with weekly cisplatin recommended for FIGO Stage I B2 - IIB

- Post Wertheim's high risk Patients : CRT

- CRT for FIGO Stage III-IVA: to be established further

Role of concomitant chemo-brachytherapy is not clearly established

Alternatives to Cisplatin: No much progress including biological agents

Adjuvant CT after CRT & Induction CT: Phase III studies ongoing

Targeted therapy / biological agents: Bevacizumab