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Definitive Chemoradiation

Consider in those

Inoperable for medical reasons

Complete R0 unlikely (T4b)

Decline surgery

Upper 1/3 Tumours

50-60Gy

If disease can be encompassed in a radical

radiotherapy volume

Herskovic NEJM, 326:1393.1992

Cooper JAMA, 281:1623-1627, 1999