761 / 815
Reactions Depend On:
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Total Dose and Total Volume of tissue irradiated
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Dose per Fraction/Treatment Time
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Treatment Planning (2D,3D,IMRT)
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Previous Treatment (ie. Sx)
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Anatomical Site (proximity to critical structures) +Individual Tolerance
Doses of normal tissues
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Other Treatment Modalities (Chemotherapy increases mucositis)
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Co Morbidities - impaired vascularity – DM , HTN